Comparison of Intraocular Pressure Lowering Effect of Travoprost and Timolol / Dorzolamide Combination in Primary Open Angle Glaucoma
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چکیده
Material and Methods: This study was conducted at outpatient department, Ophthalmology unit, Khyber Teaching Hospital, Peshawar. Study design was randomized controlled trial and (group B receiving Timolol 0.5% and Dorzolamide 2% was considered as control group) the duration of the study was 6 months in which a total of 136 patients were included. All cases included in the study were diagnosed as cases of primary open angle glaucoma. Patients were divided into two groups i.e. A and B with each group having 68 patients. Patients in group A were given Travoprost 0.004% eye drops daily and patients in group B were given eye drops having combination of Timolol 0.5% and Dorzolomide 2% twice daily. Patients were advised to come at 6 weeks interval for follow up. At each follow up visit, IOP was recorded.
منابع مشابه
Efficacy and safety of travoprost/timolol vs dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension
PURPOSE To compare the intraocular pressure- (IOP-) lowering efficacy of fixed combinations travoprost 0.004%/timolol 0.5% and dorzolamide 2%/timolol 0.5% in patients with ocular hypertension or open-angle glaucoma. METHODS In this prospective, multicenter, double-masked, randomized clinical trial, 319 qualifying patients received either travoprost/timolol once daily in the morning (n = 157) ...
متن کاملIntraocular Pressure-Lowering Effects of Commonly Used Fixed-Combination Drugs with Timolol: A Systematic Review and Meta-Analysis
BACKGROUND The first goal of medical therapy in glaucoma is to reduce intraocular pressure (IOP), and the fixed-combination medications are needed to achieve sufficiently low target IOP. The aim of this systematic review and meta-analysis is to evaluate IOP-lowering effect of the commonly used fixed-combination drugs containing 0.5% timolol. METHODS Pertinent publications were identified thro...
متن کاملCurrent Preferred Agents: BETAXOLOL, BRIMONIDINE (ALPHAGAN AND ALPHAGAN P), BRINZOLAMIDE (AZOPT), CARTEOLOL. DORZOLAMIDE/TIMOLOL, LATANOPROST, PILOCARPINE GEL AND DROPS, and TRAVOPROST (TRAVATAN Z®). Current Non-preferred Agents: ACETAZOLAMIDE, ACETYLCHOLINE CHLORIDE (MIOCHOL-E), ALPHAGAN® P, ALPRACLONIDINE (IOPIDINE), AZOPT®, BETAXOLOL
Background: The first goal of medical therapy in glaucoma is to reduce intraocular pressure (IOP), and the fixed-combination medications are needed to achieve sufficiently low target IOP. The aim of this systematic review and meta-analysis is to evaluate IOP-lowering effect of the commonly used fixed-combination drugs containing 0.5% timolol. Methods: Pertinent publications were identified thro...
متن کاملComparison of the efficacy and safety of fixed combination travoprost/timolol and dorzolamide/ timolol in patients with primary open-angle glaucoma and ocular hypertension.
INTRODUCTION Combining two medications in one bottle may improve compliance by reducing the time required to administer drops and the frequency of the total number of medication bottles. OBJECTIVE To compare the efficacy of reduced intraocular pressure (IOP) and safety of fixed combination travoprost 0.004%/timolol 0.5% vs. fixed combination dorzolamide 2%/timolol 0.5% in patients with primar...
متن کاملIntraocular pressure-lowering effects of commonly used fixed combination drugs with timolol in the management of primary open angle glaucoma.
AIM To evaluate intraocular pressure (IOP)-lowering effect and ocular tolerability of brimonidine/timolol, dorzolamide/timolol and latanoprost/timolol fixed combination therapies in the management of primary open angle glaucoma. METHODS Each drug was administered for two months, after which a circadian tonometric curve was recorded using a Goldmann applanation tonometer. Ocular discomfort (co...
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